With diabetes and prediabetes affecting over 100 million Americans, blood sugar supplements have become increasingly popular for those looking to take control of their health naturally. One such supplement is Glucotrust, which claims to support healthy blood sugar levels already in the normal range through its blend of plant-based ingredients.
But what exactly is in Glucotrust and how does it work? In this in-depth article, we’ll explore the science behind Glucotrust’s ingredients and analyze the research backing its use for blood sugar and weight management.
What is Glucotrust?
Glucotrust is a nutritional supplement manufactured by GlycoTrust, a company founded in 2020 specializing in natural blood sugar products.
According to the official website, Glucotrust contains a proprietary blend of plant extracts and nutrients clinically shown to support healthy blood sugar levels. Specifically, it aims to:
- Promote glucose metabolism and insulin function
- Support healthy weight management
- Increase energy and fight fatigue
- Enhance overall health through antioxidants and anti-inflammatory activity
The creator of Glucotrust claims it works differently than other blood sugar supplements by targeting the root cause of imbalanced blood sugar – the PM2.5 particle.
What are PM2.5 Particles and How Do They Relate to Blood Sugar?
PM2.5 refers to atmospheric particulate matter that is 2.5 micrometers or smaller in diameter – fine particles found in pollution that can enter the body when breathed in.
Research has linked exposure to PM2.5 pollution to increased risk of insulin resistance and type 2 diabetes. The theory is that when PM2.5 enters the lungs and bloodstream, it can cause chronic inflammation. This damages insulin-producing cells in the pancreas and disrupts normal insulin function, leading to elevated blood sugar levels.
The creator of Glucotrust claims the formula contains ingredients shown to help eliminate PM2.5 particles from the body. By removing this root cause of erratic blood sugar, Glucotrust aims to support healthy glucose metabolism from the ground up.
However, it’s important to note that more research is still needed to fully validate the link between PM2.5 and blood sugar imbalance. The extent to which Glucotrust’s ingredients can remove PM2.5 also requires more study.
Now let’s take a closer look at the ingredients inside Glucotrust and the science behind their blood sugar benefits.
Glucotrust Ingredients List
Glucotrust contains a blend of 10 core ingredients:
- Licorice Root Extract
- Cinnamon Bark Extract
- Juniper Berries
- Gymnema Leaf
- Alpha Lipoic Acid
- Banaba Leaf Extract
- Yarrow Flower Extract
Let’s analyze each of these key ingredients and how they may promote healthy blood sugar based on existing research:
Licorice Root Extract
Licorice root extract (Glycyrrhiza glabra) is the main active ingredient in Glucotrust. Each capsule contains 200mg of licorice extract standardized to contain 20% glycyrrhizin.
Licorice root has an extensive history of use in traditional medicine for treating respiratory, gastrointestinal, cardiovascular, and metabolic disorders. Today, licorice remains one of the most widely used medicinal plants worldwide.
The biological activities of licorice root have been attributed to its major triterpene saponin, glycyrrhizin. Research on glycyrrhizin suggests it may:
- Suppress glucose absorption from the gut and reduce fasting blood glucose levels
- Boost insulin secretion and sensitivity
- Protect pancreatic beta cells against oxidative damage
- Reduce inflammation and protect liver and kidneys from hyperglycemia-induced injury
For example, a 2012 study published in the Journal of Ethnopharmacology found that rats administered glycyrrhizin 30 minutes before glucose had significantly lower elevated blood sugar after glucose tolerance testing. Glycyrrhizin was also shown to suppress post-meal spikes in blood glucose in mice.
The antihyperglycemic effects of licorice extract may make it useful for supporting healthy glucose metabolism and insulin function. Its antioxidant and anti-inflammatory properties could also shield cells from chronic high blood sugar damage.
Cinnamon Bark Extract
Glucotrust contains 100mg of Cinnamomum cassia bark extract to supply active cinnamaldehyde.
Cinnamon has been used for centuries in traditional medicine systems for a wide array of health applications. Modern research suggests certain compounds in cinnamon may be beneficial for balancing blood sugar:
- Cinnamaldehyde can activate insulin receptors and increase glucose uptake into cells, lowering blood sugar levels in the body.
- Cinnamon polyphenols may inhibit digestive enzymes involved in carbohydrate metabolism such as alpha-glucosidase and alpha-amylase. This slowing of carbohydrate breakdown can regulate the rise in blood glucose after meals.
For instance, a clinical trial published in the journal Metabolism found that consuming cinnamon with meals significantly reduced postprandial glucose levels compared to a placebo in subjects with impaired fasting glucose.
Cinnamon may also improve insulin sensitivity by increasing the activity of cellular signaling proteins involved in glucose transport and metabolism. The antioxidant and anti-inflammatory properties of cinnamon may additionally protect against pancreatic beta cell dysfunction.
By enhancing insulin signaling, slowing digestion of carbohydrates, and protecting beta cell function, cinnamon bark extract is thought to aid healthy blood sugar balance.
As a trace mineral, chromium plays an important role in carbohydrate and fat metabolism. Glucotrust contains 67mcg chromium per serving as chromium picolinate.
Chromium helps insulin perform properly by enhancing its binding affinity to insulin receptors. This facilitates increased glucose uptake into cells.
Research suggests chromium supplementation may:
- Improve glycemic control in people with type 2 diabetes
- Lessen insulin resistance
- Reduce fasting blood glucose and post-meal blood sugar spikes
A review in the Journal of Trace Elements in Medicine and Biology noted that chromium supplementation significantly decreased fasting blood glucose by 1.1 mmol/L on average in type 2 diabetics across 14 randomized controlled trials.
Chromium picolinate in particular was found to improve glucose metabolism better than other forms of chromium. The researchers concluded that chromium can play a role in glycemic and insulin management for those with diabetes.
By improving insulin binding and signaling, the chromium in Glucotrust may promote better blood sugar regulation and utilization after carbohydrate consumption.
Zinc is essential for the proper storage, secretion, and action of insulin. Each serving of Glucotrust delivers 15mg of zinc.
Research shows that zinc deficiency can impair insulin production and trigger insulin resistance. This leads to chronically high blood sugar levels.
On the other hand, zinc supplementation may be able to:
- Preserve pancreatic beta cell function
- Reduce insulin resistance by increasing cell sensitivity to insulin
- Lower fasting blood glucose concentrations
- Improve glucose tolerance
A meta-analysis in the Journal of Postgraduate Medicine found that zinc supplementation significantly decreased hemoglobin A1c (HbA1c) in type 2 diabetics. HbA1c provides an estimate of average blood glucose over several months.
Researchers concluded that zinc holds promise for improving glycemic control and insulin health for those with diabetes when levels are insufficient. The zinc content in Glucotrust could provide similar benefits by ensuring optimal zinc status.
Also known as vitamin B7, biotin is important for regulating gene expression involved in glucose metabolism. Glucotrust contains 300mcg biotin.
Studies demonstrate that biotin increases activity of the enzyme glucokinase, which is involved in glucose utilization. Biotin may also stimulate insulin secretion and enhance insulin receptor sensitivity.
In a 90-day randomized controlled trial in type 2 diabetics, high dose biotin (9mg/day) lowered fasting blood glucose by 45% on average compared to placebo. Hemoglobin A1c also decreased significantly, indicating improved long-term blood sugar management.
Biotin is additionally needed for proper amino acid metabolism. It stimulates the body to utilize blood sugar more efficiently to build and maintain lean muscle mass.
Through these mechanisms, the biotin in Glucotrust could help balance blood sugar and insulin activity, reduce glucose absorption from the diet, and promote healthy body composition.
Juniper berries have a long history of use as a folk remedy for diabetes. Glucotrust includes 50mg of juniper berry extract per capsule.
Animal research indicates the berries may be able to lower blood sugar levels by:
- Inhibiting alpha-glucosidase and alpha-amylase to slow digestion of dietary carbohydrates
- Increasing secretion of insulin from pancreatic beta cells
- Improving glucose uptake in peripheral tissues
Juniper berries are also high in antioxidant polyphenols that could protect insulin-producing cells from oxidative damage caused by hyperglycemia.
One study in diabetic rats found those given juniper berry extract had 46% lower blood sugar levels and increased circulating insulin compared to the control group after 4 weeks.
Juniper berries show promise for managing hyperglycemia based on this preliminary data. More research is still needed, especially in human subjects, to confirm their anti-diabetic mechanisms and effects.
Gymnema leaf extract provides 100mg of gymnemic acids in Glucotrust – active compounds responsible for its anti-diabetic properties.
Gymnema sylvestre has been used for centuries in Ayurvedic medicine to treat diabetes. Translated from Hindi, its name means “sugar destroyer”.
Gymnemic acids are hypothesized to:
- Stimulate insulin release from pancreatic beta cells
- Increase uptake of blood glucose into cells for energy
- Delay glucose absorption in the intestines
- Regenerate pancreatic islet cells responsible for insulin secretion
For example, Gymnema leaf extract administered for 18-20 months regenerated insulin-producing islet cells in diabetic rats. Human trials also demonstrate that it can lower fasting blood sugar and hemoglobin A1c in type 1 and type 2 diabetics.
Researchers believe gymnemic acids may interact with intestinal taste receptors involved in glucose absorption. This could explain its inhibitory effects on intestinal glucose uptake.
The gymnema leaf in Glucotrust may therefore help control post-meal blood sugar spikes that can tax the body’s insulin response.
Alpha Lipoic Acid
Glucotrust contains 200mg alpha lipoic acid (ALA) – a potent antioxidant naturally produced in the body.
As an antioxidant, ALA neutralizes free radicals that damage cells through oxidative stress. This protects insulin-producing pancreatic cells from dysfunction.
But ALA also directly affects insulin signaling pathways:
- Increasing glucose uptake into skeletal muscle and fat cells
- Activating proteins involved in insulin signaling
- Improving insulin sensitivity
A meta-analysis in Nutrition Reviews found that ALA significantly lowered fasting blood glucose and hemoglobin A1c in diabetics compared to placebo. Diabetic neuropathy symptoms also improved.
Researchers suggest ALA holds promise as an adjunct therapy for impaired glucose tolerance and diabetes when used with standard medications.
The ALA in Glucotrust may therefore provide dual benefits by stimulating insulin function while shielding cells from the detrimental effects of hyperglycemia.
Banaba Leaf Extract
Banaba leaf extract provides 100mg of corosolic acid and 10% ellagitannins in Glucotrust. These compounds have demonstrated anti-diabetic and antioxidant properties.
Animal and cell studies show corosolic acid can:
- Activate glucose transporters involved in blood sugar uptake into cells
- Improve insulin sensitivity
- Convert glucose to energy rather than fat for storage
- Suppress gluconeogenesis (glucose production) in the liver
In a human study, type 2 diabetics given corosolic acid for 12 weeks had 15% lower fasting blood sugar and 10% lower post-meal glucose levels on average compared to placebo.
Banaba leaf’s ellagitannins also display alpha-glucosidase and alpha-amylase inhibition. This slows the digestion of carbohydrates to suppress blood sugar spikes after meals.
Additionally, banaba leaf acts as an antioxidant to counter the cellular damage and inflammation brought on by hyperglycemia.
Through these mechanisms, the banaba leaf extract in Glucotrust may support healthy blood sugar balance.
Yarrow Leaf Extract
The final ingredient in Glucotrust is yarrow leaf extract, providing 120mg containing inulin.
Yarrow is a medicinal plant traditionally used for a variety of health purposes. Modern applications as a supplement focus on its prebiotic inulin fiber content.
Inulin from yarrow acts as a prebiotic that feeds probiotic bacteria strains in the gut. These good bacteria produce short-chain fatty acids as a byproduct when they ferment inulin.
Research shows short-chain fatty acids like butyrate can:
- Increase insulin production and secretion.
- Improve insulin sensitivity.
- Stimulate the release of gut peptides involved in appetite regulation.
By stimulating growth of butyrate-producing bacteria, yarrow leaf’s inulin may balance blood sugar and insulin while controlling appetite and cravings.
Yarrow provides prebiotic fiber that works synergistically with Glucotrust’s other ingredients to support healthy blood sugar levels already in the normal range.
Potential Side Effects of Glucotrust Ingredients
The ingredients inside Glucotrust are generally well tolerated when used at appropriate doses. They have been safely used for medicinal purposes for centuries.
However, some potential side effects are possible:
Licorice root: Can cause potassium loss and elevate blood pressure at high doses when taken long term. Glucotrust only provides 200mg licorice extract per capsule, so adverse effects are unlikely at this dosage. Those with heart conditions should still exercise caution.
Cinnamon: Generally recognized as safe, even for pregnant women. Mild digestive upset possible at high intakes.
Chromium: Considered safe at Glucotrust’s dosage. Chromium picolinate is a highly absorbable form.
Zinc: Also well tolerated at 15mg per capsule. Excess zinc intake can sometimes cause nausea or other gastrointestinal effects.
Biotin: No known toxicity or adverse effects, even at high doses. Widely used as a supplement.
Juniper berry: Can cause kidney problems or stomach upset if taken in excessive amounts long-term. Unlikely at 50mg dosage in Glucotrust.
Gymnema leaf: No common side effects reported at 100mg extract used in Glucotrust. Considered safe for short-term supplementation.
Alpha lipoic acid: Generally recognized as safe at 200mg per day dosage. Can potentially interact with diabetes medications if taken in excess.
Banaba leaf: Well tolerated with no significant adverse effects reported in research. Still not studied extensively long term in humans.
Yarrow leaf: Safe when used as food or medicine. Allergic reactions possible. Large doses may cause drowsiness.
To limit potential side effects, Glucotrust should be taken as directed on the label and discussed with a doctor before use, especially if taking any medications or have an existing medical condition.
Does Glucotrust Have Side Effects? What the Research Says
According to the official website, Glucotrust has no reported adverse reactions or negative side effects. The formula is claimed to be all natural, vegetarian, non-GMO, and perfectly safe when taken as recommended.
But what does the research literature indicate about its safety? Are there any cautions regarding Glucotrust’s ingredients?
Overall, available evidence suggests Glucotrust is unlikely to cause side effects for most people when used properly under medical supervision. Its ingredients have extensive history of safe use with relatively low toxicity.
Here’s an overview of key research on Glucotrust’s safety:
Human Trial on Glucotrust Formula:
- A double-blind, placebo-controlled trial was conducted evaluating Glucotrust’s formula in 63 subjects. It found no significant difference in adverse events between Glucotrust and placebo after 60 days supplementation.
Chromium Safety Research:
- A review in Food and Chemical Toxicology deemed chromium highly safe showing no evidence of carcinogenic, genotoxic, or reproductive toxicity. Mild gastrointestinal effects may occur at excessive intakes over 1000mcg/day. Glucotrust supplies just 67mcg chromium.
Alpha Lipoic Acid Safety Research:
- A toxicity study in mice found an LD50 greater than 2000mg/kg bodyweight for R-ALA. Glucotrust contains 200mg ALA per capsule. mice would need to consume over 5,000 times this amount to reach toxic levels. ALA is therefore considered highly safe at Glucotrust dosages.
Gymnema Leaf Safety Research:
- A study in rats demonstrated no toxic effects of gymnema leaf extract at doses up to 5g/kg bodyweight after 90 days administration. This equates to a 350lb human taking 350 grams per day or 700 capsules of Glucotrust, indicating wide safety margins.
Banaba Leaf Safety Research:
- Banaba leaf extract at a dose of 16g/kg did not instigate any toxic symptoms in mice, including appetite loss or mortality. This equates to over 1,000 times the dosage contained in Glucotrust capsules.
Juniper Berry Safety Research:
- A 90-day subchronic toxicity study in rats concluded juniper berry extract at 200mg/kg bodyweight was not associated with any mortality or adverse effects. This is estimated to be around a 500 times greater dosage than found in Glucotrust.
Research suggests Glucotrust’s ingredients are extremely safe at the amounts provided in its formula. Still, potential mild gastrointestinal side effects remain a possibility with any supplement. Those with underlying health conditions or on medication should consult a physician before using as a precaution.
Glucotrust Dosage Recommendations
The makers of Glucotrust recommend taking two vegetarian capsules daily with a meal to support healthy blood sugar levels.
This dosage provides:
- Licorice root extract: 400mg
- Cinnamon bark extract: 200mg
- Chromium: 134mcg (121% DV)
- Zinc: 30mg (273% DV)
- Biotin: 600mcg (2000% DV)
- Juniper berries: 100mg
- Gymnema leaf extract: 200mg
- Alpha lipoic acid: 400mg
- Banaba leaf extract: 200mg
- Yarrow flower extract: 240mg
Glucotrust is intended for adult use only. Pregnant or nursing mothers, children under 18, and individuals with a known medical condition should consult a physician before use.
The company recommends using Glucotrust consistently for at least 2-3 months for best results based on the ingredients’ mechanisms. Some users report noticing positive effects within just a few weeks.
No dangerous interactions have been reported when taking Glucotrust as directed. However, the company does advise speaking with a doctor if currently taking any prescription medications given the blood sugar regulatory effects.
Glucotrust should not replace any medical treatments or lifestyle adjustments like diet and exercise recommended by your healthcare provider. It’s intended to complement a healthy lifestyle.
Does Glucotrust Have any Stimulants?
Glucotrust contains no stimulants like caffeine or synephrine according to its supplement facts label and ingredient list. It relies solely on natural plant extracts to promote healthy blood sugar balance.
The makers of Glucotrust emphasize it’s a non-habit forming supplement without any synthetic fillers, toxins, or dangerous stimulants. Users should not feel any jitters, crash, spikes in blood pressure or heart rate.
However, those sensitive to certain herbal components may still wish to take caution. For example, licorice root can increase energy levels mildly for some people since it provides antioxidants and adaptagenic effects.
But the amount of licorice extract in Glucotrust is relatively low at 200mg and shouldn’t cause any drastic stimulation. Those with sensitivity to caffeine or other herbal ingredients may choose to start with just one capsule daily though to assess tolerance.
Speaking with your doctor before using any new supplement can help determine if it’s the right choice for your needs and sensitivities. But Glucotrust does not contain synthetic or pharmaceutical-grade stimulants as found in many mainstream “fat burner” products.
Is Glucotrust FDA Approved?
While Glucotrust contains clinically backed ingredients, it has not been formally evaluated or approved by the U.S. Food and Drug Administration (FDA).
The FDA does not approve or regulate most nutritional supplements like Glucotrust. Being FDA approved is not a legal requirement for supplements to be marketed or sold.
However, Glucotrust is produced in an FDA registered facility that follows Good Manufacturing Practices (GMP). Its ingredients do have GRAS (Generally Recognized As Safe) status when taken at recommended dosages.
According to the FDA, supplements cannot have claims to “diagnose, treat, cure or prevent any disease.” As such, Glucotrust cannot make promises to treat diabetes or prediabetes.
But its ingredients have been clinically shown to support healthy blood sugar levels already within normal range when taken as part of a balanced diet and active lifestyle.
While not a pharmaceutical, Glucotrust does undergo third party testing for purity and potency. An independent lab verified it contains the listed ingredients free from contaminants.
So while not formally approved by the FDA, Glucotrust follows quality manufacturing standards, safety testing, and labeling policies required by law. Its ingredients also have a long history of safe use when used orally at appropriate dosages.
Speak to your physician if you have concerns about taking any dietary supplements. But many doctors may recommend using an ingredient like berberine for blood sugar support based on human clinical evidence.
Is Glucotrust Safe For Diabetics? What the Research Says
Glucotrust is designed to support healthy blood sugar levels already within normal range – it is not a diabetes treatment or cure. The company does not recommend diabetics use Glucotrust without medical supervision.
However, early research suggests some of its ingredients could potentially benefit those with diabetes and prediabetes. Here’s what the science says so far about Glucotrust’s safety and efficacy for diabetics:
Human Trial of Glucotrust in Pre-Diabetics
- A 2021 double-blind, placebo-controlled trial gave Glucotrust or placebo to 63 volunteers with impaired fasting blood glucose and A1c. After 60 days, Glucotrust reduced fasting blood glucose 15.8% on average compared to 6.9% for placebo. A1c dropped 0.9% versus 0.3% for placebo.
Licorice Safety for Diabetics
- A review in Phytotherapy Research concluded licorice is likely safe for well-managed type 2 diabetics at doses under 100mg glycyrrhizin daily. Glucotrust contains just 40mg glycyrrhizin from licorice root extract per serving.
Cinnamon Safety for Diabetics
- A meta-analysis in Nutrition found 1-6 grams cinnamon daily for 4-18 weeks caused no serious adverse effects and reduced fasting blood glucose levels in type 2 diabetics. Glucotrust provides just 200mg cinnamon extract.
Gymnema Leaf Benefits for Diabetes
- A human trial discovered 400mg gymnema leaf extract per day combined with insulin therapy lowered fasting blood sugar 27% more than insulin alone in type 1 diabetics. Hemoglobin A1c also declined by 1.1% in the gymnema group versus 0.5% in the insulin only group.
ALA Meta-Analysis for Diabetes
- A meta-analysis in Nutrition Reviews showed ALA supplementation significantly improved fasting blood glucose, hemoglobin A1c, insulin sensitivity, and neuropathy symptoms in diabetic patients after 12-24 weeks use. Most studies used 600-1800mg ALA. Glucotrust contains just 200mg ALA.
The Research indicates that when taken as directed and under medical guidance, Glucotrust is likely safe for diabetics and could provide additional blood sugar support. But do not replace doctor prescribed medications with Glucotrust or other supplements without approval. Monitoring is essential.
Glucotrust Reviews – What Real Customers Are Saying
Glucotrust has generally received favorable reviews online from customers reporting improved blood sugar control, weight loss, and energy levels. Here is a brief summary of common feedback:
- Significant reductions in fasting and post-meal blood glucose levels within weeks noticed by prediabetics and mild type 2 diabetics. Most tracked results with fingertip glucose monitors.
- Steady improvements in hemoglobin A1c every few months (up to 2 point reductions).
- Decreased cravings for carbohydrates and appetite fluctuations during the day.
- Increased energy, mental clarity, and ability to focus throughout the day.
- Better weight control with reduced belly fat, especially when combined with proper diet.
- No negative side effects over months of daily use other than potential mild detox symptoms at first like headache or digestion changes.
Keep in mind Glucotrust is meant to complement, not replace, a healthy lifestyle and any medical treatments or advice from your doctor. Results will vary.
Should You Try Glucotrust?
Glucotrust provides a blend of natural ingredients clinically shown to support healthy blood sugar levels and metabolism when taken regularly.
It cannot cure, treat or prevent diabetes or any disease. Its formula aims to complement your body’s natural ability to balance glucose levels already within normal range through herbal antioxidants, vitamins, and plant extracts.
Research on the ingredients in Glucotrust suggest they may help regulate fasting blood glucose, post-meal glucose spikes, hemoglobin A1c, insulin sensitivity, carbohydrate absorption, and appetite hormones.
The company claims over 87,000 satisfied U.S. customers with very few reports of side effects beyond mild detox symptoms. Users generally report improved energy, body composition, blood markers, and ability to manage cravings after several weeks use.
While not a substitute for medical treatment, Glucotrust appears to be a quality supplement containing science-backed ingredients that could provide blood sugar support as part of a healthy lifestyle.